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Thyroid Science 1(12):DB1-DB8, 2006

The Linguistic Etiologies of
Thyroxine-Resistant Hypothyroidism

Eric K. Pritchard

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Contact: Eric Pritchard,

ABSTRACT. The thyroxine resistant victims of hypothyroidism are not suffering because there is no treatment available—the Food and Drug Administration approved and indicated them long ago. These victims are suffering because the proper treatments are not considered—linguistic etiologies keep the science of "exo-endocrine" (outside of the endocrine system) hypothyroidism beyond the reach of the practicing physician with the confusion of "overinclusion" (identical treatment of two classes that burdens one excessively). This confusion begins with two definitions for "hypothyroidism," thyroid-centric" and "symptom-oriented," which are related to thyroxine (T4) and triiodothyronine (T3), respectively. Although the hypothyroidism paradigm concentrates upon the thyroid and thyroxine, the active hormone in the tissue cells is triiodothyronine. The claimed intimate relationship between inadequate thyroid secretion and the symptoms of hypothyroidism has been distanced by scientific discoveries of exo-endocrine hormone operations. Symptoms do not imply endo-endocrine (within the endocrine system) etiologies only anymore.

The confusion of overinclusion hides the exo-endocrine hormone operations, their potential for failure, and their importance. Different hormones and etiologies demand different diagnostics and hormone supplements.

The confusion of overinclusion continues in the coverup for thyroxine-resistant treatment failures. Counter intuitively and contrary to research, laboratory assays and the exo-endocrine hormone operations are declared infallible. Fallacious logic reassigns continuing symptoms to "normal" somatic etiologies. Definition confusion allows endo-endocrine test results to be erroneously applied to exo-endocrine etiologies.

Baisier, et al., published an empirical study of thyroxine resistant patients and found success in using an indicated, FDA approved, and available therapy. These sufferers need the resolution of this confusion so they can regain their lives. The linguistic etiologies must be eliminated so that people needing different treatments are treated differently and properly.

KEY WORDS. hypothyroidism, exo-endocrine, thyroxine-resistant, Baisier, continuing symptoms, basal temperature, nonspecific symptoms, combination therapy, guideline, overinclusion.

Pritchard, E.K.: The linguistic etiologies of thyroxine-resistant
hypothyroidism. Thyroid Science, 1(12):DB1-DB8, 2006.

(Full Text Free in pdf format)

© 2006 Thyroid Science