Thyroid Science 3(2):CLS1-2, 2008
Fine-Needle Aspiration of the Thyroid Gland—Its Role
in the Investigation of Thyroid Autoimmunity
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P.O. Sandberg, MD,
*Aleris Medilab, Täby Sweden Contact:
John C. Lowe, MA, DC, Editor-in-Chief
editorial, I described the important clinical work and research on
autoimmune thyroiditis that Dr. Bo Wikland and his colleagues are
conducting in Stockholm, Sweden. Since the editorial, Dr. Wikland has
generously written two papers for Thyroid Science. In
paper, he describes hypothyroidism caused by autoimmune
thyroiditis in patients with "normal" blood test results, a condition he
and his colleagues call "subchemical hypothyroidism." In
his second paper,
he presents an important hypothesis: that with these patients—who are clinically hypothyroid, biochemically
euthyroid, but have laboratory evidence of autoimmune thyroiditis—we must
suppress their TSH levels to stop the pathological activity in the thyroid
gland and relieve their symptoms.
Now we are privileged to publish a highly informative paper that dovetails
with his. It is written by Dr. P.O. Sandberg, a clinical and research
colleague of Dr. Wikland's in Stockholm. Dr. Sandberg is a cytopathologist. In working with Dr. Wikland, he examines thyroid gland
tissue samples in her laboratory for evidence of autoimmune thyroid
In his paper, Dr. Sandberg explains the importance of examining tissue
samples for structural evidence of autoimmune disease. He also shows us,
in a photograph of lymphocyte-invaded thyroid tissues, what he often sees
in tissue samples from afflicted patients.
Dr. Sandberg comments on the relative contributions of different
procedures used in the diagnostic workups of thyroiditis patients.
He discusses the features to look for during palpation of the thyroid
gland, and what ultrasound may reveal both before and during its use in
guiding fine-needle aspiration.
Dr. Sandberg’s paper provides an extraordinary learning opportunity for
those of us who haven’t spent time with a cytopathologist in his or her
lab. Most importantly, though, is that he makes clear the importance of
fine-needle aspiration and the need for the involvement of more cytopathologists in
patients’ diagnostic workups. We are grateful to him for contributing this
important paper to Thyroid Science.
Autoimmune thyroid disease • Chronic fatigue • Cytopathology • Fine-needle
aspiration • Ultrasonography
*Thanks to our
Executive Editor, Jackie Yellin, for
enabling us to expeditiously publish Dr. Sandberg’s paper.
Fine-Needle Aspiration of the Thyroid Gland:
Its Role in the Investigation of Thyroid Autoimmunity.
Science, 3(2):CLS1-2, 2008.
Text Free in pdf format)
© 2008 Thyroid Science